Resources for you and
your patients

See below for resources that you can download—a comprehensive brochure, ICD-10 codes
for chronic idiopathic constipation (CIC), an access & support tool, and more.

 

Hear from a Leading Expert

Dr. Brian E. Lacy, Professor of Medicine, Mayo Clinic, shares his insights on a
typical patient with CIC, Motegrity clinical data, and how Motegrity works.

Now playing

8:31
A Candidate for Motegrity

Now playing

12:15
Clinical Overview

Now playing

7:45
Mechanism of Action

HCP Resources

Prokinetic
Patient ID Tool

Determine if your patients may be looking for a different treatment approach.

Download

Access &
Support Tool

Help patients access insurance and savings information.

Download
Map icon

Comprehensive
Brochure

Download this brochure to review the MOA, efficacy, and safety profile and more information on Motegrity.

Download

ICD-10 Code

Use this code to complete the prescription records for your patients with CIC.

ICD-10 code: K59.04

HCP Resources

Prokinetic
Patient ID Tool

Determine if your patients may be looking for a different treatment approach.

Download
Map icon

Comprehensive
Brochure

Download this brochure to review the MOA, efficacy, and safety profile and more information on Motegrity.

Download

Access &
Support Tool

Help patients access insurance and savings information.

Download

ICD-10 Code

Use this code to complete the prescription records for your patients with CIC.

ICD-10 code: K59.04

National Library of Medicine

Efficacy and Safety of Prucalopride in Chronic Constipation: An Integrated Analysis of Six Randomized, Controlled Clinical Trials

Read the Full Study

Patient Resources

Patient Expectation Guide

Use this guide to learn how Motegrity works, what to
expect when taking Motegrity, and read real patient stories
taking Motegrity and their journey with CIC.

Download

Doctor Discussion Guide

This guide may help enable patients to have a meaningful
discussion with their HCP.

Download

Motegrity Digital Patient
Waiting Room Brochure

Learn how Motegrity works, what to expect when taking
Motegrity, and how to start a conversation with
your doctor.

Download

IMPORTANT SAFETY INFORMATION

Expand Collapse

Please expand for Indication and Important Safety Information.

Contraindications

  • Hypersensitivity to Motegrity. Reactions including dyspnea, rash, pruritus, urticaria, and facial edema have been observed
  • Intestinal perforation or obstruction due to structural or functional disorder of the gut wall, obstructive ileus, severe inflammatory conditions of the intestinal tract such as Crohn's disease, ulcerative colitis, and toxic megacolon/megarectum

Warnings and Precautions

Suicidal Ideation and Behavior: In clinical trials, suicides, suicide attempts and suicidal ideation have been reported. Postmarketing cases of suicidal ideation and behavior as well as self-injurious ideation and new onset or worsening of depression have been reported within the first few weeks of starting Motegrity. A causal association between treatment with Motegrity and an increased risk of suicidal ideation and behavior has not been established. Monitor patients for new onset or worsening of depression and emergence of suicidal thoughts and behavior. Instruct patients to discontinue Motegrity immediately and contact their healthcare provider if they experience any of these symptoms.

Adverse Reactions

Most common adverse reactions (≥2%) are headache, abdominal pain, nausea, diarrhea, abdominal distension, dizziness, vomiting, flatulence, and fatigue.

Use in Specific Populations

  • Lactation: Motegrity is present in breast milk. Consider risks and benefits of breastfeeding
  • Pediatric: Safety and effectiveness in pediatric patients have not been established
  • Renal Impairment: A decreased dosage is recommended in patients with severe renal impairment. Avoid Motegrity in patients with end-stage renal disease requiring dialysis

INDICATION

Motegrity® (prucalopride) is a serotonin-4 (5-HT4) receptor agonist indicated for the treatment of chronic idiopathic constipation (CIC) in adults.

Please click here for full Prescribing Information.

References:

1. ICD-10-CM Tabular List of Diseases and Injuries. https://www.cms.gov/Medicare/Coding/ICD10/2020-ICD-10-CM. Accessed March 3, 2020.